Beyond the Abstract

Beyond the Abstract

beyondtheabstract.captivate.fm
Science and research for everyone


CRISPR: All About That Base (Editing)
Jul 9 • 21 min
CRISPR is a genome-editing technology that has revolutionized medical research and created new therapies for previously incurable diseases. But what is CRISPR exactly, where does it come from, and how does it work? In this episode of Beyond the Abstract,…
A (Cytokine) Storm is Brewing
May 4 • 24 min
COVID-19 is a devastating disease, and the elderly and those with chronic medical conditions are especially at risk. But why is it that some seemingly healthy people also get so sick that they have to be put on a ventilator? The answer may lie in our…
Panic at the DisCOVID
Apr 13 • 23 min
In the midst of the coronavirus pandemic, a lot remains unknown about SARS-CoV-2, the virus causing COVID-19. While we race to understand the true nature of the virus and create a vaccine, our best defense against the pandemic is social distancing.…
Bubble Lamb
Mar 26 • 26 min
Extremely premature infants are those that are born at less than 28 weeks, and often weigh less than two pounds at birth. Medical advancements have pushed the limits of viability to permit survival of infants at 22-23 weeks, but these infants suffer from…
Novel Coronavirus 2019 (2019-nCoV)
Feb 12 • 26 min
The novel coronavirus 2019 (2019-nCoV) is a respiratory virus originating from Wuhan, China that has spread to many countries, causing an outbreak. Headlines on its rapid spread have dominated media and news sites globally, and a lot remains unknown about…
The Golden Phage
Feb 3 • 32 min
Alcoholic hepatitis is a severe, life-threatening type of liver disease, but not for all patients. Some patients seem to have worse outcomes than others, but what differentiates these patients and how do we treat them? In this episode, Derek and Ellen…
The Cancer Conundrum
Jan 14 • 23 min
One in eight women will be diagnosed with invasive breast cancer, but how exactly breast cancer metastasizes and spreads to other organs still isn’t clear. E-cadherin is a protein that acts as ‘molecular glue’ that helps cancer cells stick together, but…
Achy Breaky Cytoskeleton
Jan 2 • 29 min
Your heart beats over 100,000 times a day and over 2 billion times a lifetime. The heart keeps up with wear and tear because it has a strong yet flexible cytoskeleton, the ‘framework’ of the cell. But what happens when the cytoskeleton malfunctions, and…
The Clot Thickens
Dec 11, 2019 • 38 min
Deep vein thromboses (DVTs) are clots in the blood system that can travel from the legs to the lungs, causing severe damage and even death. This week on Beyond the Abstract, Ellen and Derek are joined by John Welsh, PhD as they dive into John’s recent…
(Cilia) Size Matters
Nov 26, 2019 • 34 min
On this episode of Beyond the Abstract, Derek and Ellen invite Lindsey Avery Fitzsimons, a PhD student at the University of Maine, to discuss new research in the intersecting worlds of heart valve disease and cell biology. A new paper combining mouse…
An Astrocyte is Born
Nov 12, 2019 • 32 min
This week on Beyond the Abstract, Derek, Ellen, and fellow MD/PhD classmate Jacob are talking about Parkinson’s disease. A recent paper highlights how a new drug targets astrocytes and microglia, two types of brain cells, in order to treat Parkinson’s…
Franken-organs
Oct 30, 2019 • 28 min
In this inaugural episode of Beyond the Abstract, our hosts Ellen and Derek along with their guest and fellow MD/PhD classmate Jenna discuss a paper on interspecies chimeras to create “Franken-organs.” They discuss the potential medical implications of…