Improbable Developments

Improbable Developments
The human stories behind the medicines

Lynne Becker: Re-empowering TBI Patients
Oct 13 • 52 min
Put me in the game coach. These six simple words can be putting athletes, soldiers, and employees at great risk. Lynne Becker knows this from her experience building a database of traumatic brain injuries (TBI) for the department of defense. A bit closer…
Mike Wenger: Improving Clinical Trial Data Transparency
Sep 15 • 30 min
Mike Wenger is Vice President of Patient Engagement at TrialScope. A brain tumor patient and software developer, Mike is passionate about patient access to clinical trials. He is spearheading TrialScope Connect, the industry’s first patient referral…
Mary Rofael, MD: Helping Companies Communicate Complex Data in Ways that Matter
Jun 29 • 25 min
“I think it is really important for the public and the patient Community to learn a little more about FDA advisory committees because these are public meetings and they’re accessible for anyone to attend and learn from.” Mary Rofael, MD An FDA Advisory…
Rob Lambkin-Williams: Mapping Out the Quest for a COVID Vaccine
May 7 • 36 min
The impact of COVID-19 is literally being felt around the world. Humanity has been racing to find weapons to fight this invisible enemy. We know so very little about how the virus is operating. This can leave us feeling confused and isolated. We speak to…
Kieran Geoghegan: Life of a Scientist
Mar 25 • 43 min
“For me it was a question of dying and going to heaven for 32 years.” Dr. Kieran Geoghegan was inspired by the scientific and technological breakthroughs of the NASA programs in the 1960’s. This became a lifelong quest to get to the bottom of things and…
Robert Weker: Against All Odds
Feb 11 • 46 min
Rob Weker’s story is remarkable for many reasons. First and foremost, he has beaten cancer. Not once. Not twice. But three times. Getting the third diagnosis, this time it was pancreatic cancer, really got his attention. Only 7% of pancreatic patients…
Carol Marzetta: Living to Help Other People
Jan 14 • 29 min
This month listen to Dr. Carol Marzetta talk about how the urge to help other people has shaped her career and her life. From her earliest days as a Discovery Biologist, she has found he passion in work that tries to help people in need. She shares with…
Donald Kirsch: Getting to Know a Drug Hunter
Dec 10, 2019 • 37 min
We’ve all been there. You are at a party and someone asks, “So, what do you do?” Dr. Kirsch always found it hard to explain his career as a discovery scientist. He decided to write a book about it. ( is a colorful, fact-filled…
David Pearce: Hope Can Be Curative.
Nov 18, 2019 • 29 min
Today we hear from David Pearce, PhD, President of Innovation and Research, IRDiRC ( Dr. Pearce’s rare disease background emanates from publishing over 100 research papers on Batten Disease. David talks to us about how he got…
Kyle Bryant: Remember Why We Are Doing All This
Oct 9, 2019 • 34 min
we welcome Kyle Bryant of the Friedreich’s Ataxia Research Alliance (FARA) to discuss his journey as a patient with Friedreich’s Ataxia (FA), as an active patient leader, and in his job as a liaison between the FA community and researchers. After being…
David Fajgenbaum, MD, MBA, MSC, FCPP
Sep 9, 2019 • 36 min
We are honored to have Dr. David Fajgenbaum as our first guest on Improbable Develoipments. His story is intense. Before he even earned is medical degree, he was faced by a rare life-threatening illness for which there was no treatment, let alone cure.…
Welcome to Improbable Developments!
Sep 1, 2019 • 10 min
In this, our first episode, Kevin lays out the objectives and plan for the Improbable Developments podcast. He also shares a personal story about an innovative medicine he worked on earlier in his career, Geodon.