The Genetics Podcast

The Genetics Podcast
Exploring all things genetics. Cambridge University Alumnus and current CEO of Sano Genetics Dr Patrick Short analyses the science, interviews the experts and helps share the stories of people who have been personally affected by genetic conditions. To take part in the latest research studies mentioned in this podcast please visit

38 Big Data in genomics - why we need ‘the cloud’ and AI to make sense of it all with Dr Maria Chatzou Dunford
Jun 30 • 38 min
Genomic data, is big data - so how do we actually make sense of this huge amount of data? And why should we use 'the cloud’ to store and analyse it? We discuss how the cloud enables faster, safer, and less expensive genomic data analysis, and what the…
37 The future of medical research post COVID
Jun 10 • 44 min
This episode covers some of the dramatic changes in the field of medical research as a result of COVID19 making it unsafe for people to visit medical research facilities, and medical professional's time and efforts being redirected to fighting the new…
36 Genomics England CEO Chris Wigley & Clinical Lead Richard Scott: sequencing 35,000 people with COVID19, the future of genomic medicine, and why patients are their ‘north star’
May 27 • 25 min
Why do some people have a severe response to COVID-19, and others seem to have no symptoms at all? Is the answer in our genes? This week we talk to Chris Wigley, the CEO of Genomics England and Interim SRO for Data-NHSX, and Dr Richard Scott, the clinical…
35 8 weeks in - what it’s like to have COVID-19 with Adelina Chalmers
May 13 • 39 min
This week we talk about COVID19 and what it’s really like to have the virus. Talking to Adelina Chalmers, who first started experiencing symptoms 8 weeks ago - and was admitted to the hospital 6 weeks ago - talks about how it has been mis-sold as being…
34 1 in 70 million - conversation with rare disease advocate David Rose
Apr 29 • 28 min
What’s it like having a disease so rare, you’re misdiagnosed? Or you’re the only one in the whole of the UK to have it? David Rose is a rare disease advocate, an ambassador for Great Ormond Street Hospital, and part of the team at Rare Revolution…
33 Kat Arney on cancer research, epigenetics, and helping launch the ZOE app in the COVID19 crisis
Apr 15 • 48 min
How do you go from a cell to a baby? This question fixated Kat Arney at the beginning of her career, and pushed her towards epigenetics ‘before it was cool’. From travelling the globe asking how genes work, to her upcoming book ‘Rebel Cell’, she discusses…
32 DNA sequencing to find our roots and solve cold cases, the ethics of DNA databases with Debbie Kennett
Apr 1 • 44 min
Through combining genealogy with DNA testing, more can be discovered about family relationships - making it a powerful tool for reuniting families, and even solving cold cases. This week, Patrick interviews Debbie Kennett - a genetic genealogist at the…
31 COVID-19 - the human response to the virus, and what the future may hold with Columbia University Virologist Dr Angela Rasmussen
Mar 20 • 46 min
In this week’s bonus episode we talk to Dr Angela Rasmussen (@angie_rasmussen), a Virologist at Columbia University. She answers top questions surrounding COVID-19 and what this outbreak could mean for our future. Does genetics or blood type may affect…
30 Patient powered research networks - the future of medical research with Jillian Hastings Ward
Mar 17 • 40 min
Today, Jillian Hastings Ward is a leader in the 100,000 genomes project, but she and her family started off as one of the first families whose DNA was sequenced by the project in 2015. She talks to Patrick about her son, Sam, who was one of the first…
29 Is breath testing the new frontier in preventive medicine? Conversation with Billy Boyle, Founder and CEO of Owlstone Medical
Mar 4 • 36 min
Early detection for diseases like cancer is important to everyone, but Owlstone Medical is leading the pack by creating a breathalyser that aims to diagnose diseases in the ultimate non-invasive test. Their ground-breaking technology is completely…
28 Drug repurposing for rare disease and the future of health with Dr Bruce Bloom (CCO of Healx) and Dr Mike Tranfaglia (CSO of FRAXA)
Feb 19 • 60 min
In this double-bill episode, Patrick talks to two key rare disease researchers in the field: Dr Bruce Bloom, the CCO of Healx, and Dr Mike Tranfaglia, CSO of FRAXA. In this episode both draw on their wide-ranging personal and professional experiences to…
27 From Big Data to New Medicines with Dr Jeff Barrett, CSO of Genomics PLC
Feb 6 • 35 min
Patrick interviews Dr Jeff Barrett from Genomics PLC about how genetic data can be used for drug discovery and the future of precision medicine. In this episode, Dr Barrett talks about going beyond genes to understand how they affect particular genetic…
26 Dr Matt Might: Ultra-rare disease advocate, precision medicine researcher, and Obama advisor
Jan 23 • 45 min
Patrick interviews Dr Matt Might, whose personal and professional life has brought him all the way to advising Obama and setting up his own institute. In this exciting episode, Matt discusses how he went from a computer scientist to becoming significantly…
25 Ethics of DNA Marketplaces and Data Sharing with Dr Mahsa Shabani
Dec 23, 2019 • 36 min
Patrick talks to Dr Mahsa Shabani, a researcher at the Centre for Biomedical Ethics and Law, University of Leuven. From the golden state killer to blockchain, they discuss the latest ethical issues in genetics. They look at data sharing and involvement of…
24 Diagnosis to clinical trial in 6 weeks with Gemma Stunt
Dec 6, 2019 • 43 min
Dr Patrick Short talks to Gemma Stunt about her son Bertie’s diagnosis of Duchenne muscular dystrophy, how to get involved in clinical trials and what life is really like with a currently ‘incurable’ genetic condition.
23 Microbiome in birth and health with Dr Yan Shao
Nov 21, 2019 • 34 min
Our guest this week is Dr Yan Shao from The Wellcome Sanger Institute, a non-profit British genomics and genetics research institute. In this episode, Dr Shao discusses the findings from his most recent study; where he and his team found significant…
22 Behind every data point is a person with Dr Paul Wicks
Oct 29, 2019 • 60 min
Get to know a little bit more about our new scientific advisor Dr Paul Wicks. Paul has dedicated much of his career to patient-centric research and building patient communities, particularly in rare disease. Paul has spent 17 years in the digital health…
21 The Genetics of Alzheimer’s with Dash Genomics and HealthLytix
Oct 8, 2019 • 38 min
This week on our podcast, we speak to Xing Xu from Dash Genomics and Renee George from HealthLytix about Alzheimer’s disease. Dash Genomics has partnered with HealthLytix to produce a new model that helps you understand your individual risk of Alzheimer’s…
20 Ring Chromosome 20 Syndrome with Allison Watson
Oct 4, 2019 • 46 min
In this episode Patrick Short speaks with Allison Watson the co-founder and secretary of Ring20 Research and Support UK patient organisation and the co-chair of EpiCARE’s patient advisory group. Allison discusses the Ring Chromosome 20 syndrome and the…
19 Dr Patrick Short Discusses the Personalised Genomics Industry
Sep 25, 2019 • 30 min
This episode was originally recorded for CUTalks, the podcast of the Cambridge University Technology & Enterprise club. In this podcast, CEO and Co-founder Dr Patrick Short discusses the personalised genomics industry, as well as his journey from PhD to…
18 Elin Haf Davies: How Aparito Uses Wearables & Mobile Apps to Run Patient-Centric Clinical Trials
Sep 19, 2019 • 36 min
Our guest this week is Elin Haf Davies, who is the CEO of Aparito - a technology company that focuses on patient-generated health data. Elin is also an inspirational speaker, trans-atlantic rower and pediatric nurse. In this episode we discuss clinical…
17 Genetics News (September 2019)
Sep 10, 2019 • 24 min
Last week, the shocking story that sick migrants undergoing lifesaving care can now be deported hit the NY times - but what effect will it have on clinical trials in America? Find out in this episode of our podcast, where we discuss the top four genetic…
16 Policy Development and Patient Engagement for Rare Disease with Alistair Kent
Sep 6, 2019 • 67 min
This week on our podcast, we speak to Alastair Kent, a world leader in policy development and patient engagement for rare disease. In this episode, we discuss how research is changing in rare conditions and what part DNA sequencing and data sharing are…
15 DNA Today host Kira Dineen discusses Genetic Counselling
Aug 23, 2019 • 34 min
This week on our podcast we speak to Kira Dineen, a genetic counsellor in training and host of DNA Today. We ask Kira what she’s learned from more than 200 hours of conversation with leading doctors and researchers in genetics, as well as some questions…
14 Genetics News
Aug 21, 2019 • 29 min
In this episode, we cover the latest genetics news stories including; 1) 23andMe’s plan to start collecting health data 2) New research that’s sounding alarm bells about the accuracy of genotyping tests 3) The largest-ever study of genetics and PTSD 4) A…
13 How Eurocentricity is holding genetics back with Dr. Alicia Martin
Aug 13, 2019 • 34 min
Dr. Alicia Martin, a researcher at the Massachusets General Hospital and the Broad Institute of MIT and Harvard, discusses the issues surrounding Eurocentricity in genetics studies.
12 Q&A: Quora’s Top Genetics Questions
Aug 6, 2019 • 10 min
Dr Patrick Short answers the top genetic questions on quora. Which include: 1) How reliable is the DNA testing offered by sites like or 23andMe? 2) Does DNA testing for diet and fitness really work? 3) Does 23andMe provide accurate results…
11 Neil Bennett, Director of Research at Action Duchenne
Jul 31, 2019 • 12 min
We recently held an event bringing together charities and patient registries to help them take the next step in doing genetic research. One of our speakers was Neil Bennett, the Director of Research at Action Duchenne and he discussed how they set up a…
10 Eric Topol on how Machine Learning & AI can Contribute to the Future of Healthcare
Jul 23, 2019 • 38 min
We had the pleasure of speaking with Dr Eric Topol, author of ‘The Patient Will See You Now’ and ‘Deep Medicine’. Eric has had an incredible career which has been largely focused on researching cardiovascular disease and heart attacks, both of which he…
9 Conversation with Gencove CEO & Human Genetics Researcher Joe Pickrell
Jul 16, 2019 • 35 min
Human Genetics Researcher Joe Pickrell is the CEO of Gencove who offer low-pass sequencing technology which is both cost-efficient and provides highly accurate variant calls across the whole genome. Having trained as a statistical geneticist, Joe…
8 Dr Sonya Abraham on biologics, arthritis and the gut microbiome
Jul 9, 2019 • 17 min
Sano Genetics CEO Dr Patrick Short interviews Dr Sonya Abraham, a researcher at Imperial College, London who looks at different conditions like arthritis and psoriasis to discuss biological therapies (or biologics) and how the gut microbiome affects these…
7 creator Lasse Folkersen discusses his passion project
Jul 2, 2019 • 28 min
Lasse Folkersen discusses how he started as a passion project, out of sheer curiosity to understand his own genes and to help others with the same intention and as a result, he has now sequenced his entire living family. We discuss’s…
6 The Phlebotomist Depicts a Dystopian Future Governed by DNA Testing
Jun 18, 2019 • 26 min
The Phlebotomist is a play written by Ella Road which imagines a future where your genetic rating influences every aspect of your life and is determined through a single blood test. We spoke with Ella to find out about her inspiration and the cross overs…
5 Could Weed Killer Cure This Rare Disease (Alkaptonuria)?
Jun 11, 2019 • 26 min
We talk to Nick Sireau (co-founder of Findacure and chairman of the AKU society) about his two sons, who were both born with Alkaptonuria which is an ultra-rare genetic condition that causes the bone’s surface to turn black and corrode. Nick has worked…
4 The Genetics of Depression
May 29, 2019 • 27 min
Dr Cathryn Lewis is a highly regarded Professor of Genetic Epidemiology and Statistics at King’s College London. Previously in her career Dr Lewis significantly contributed to research on the breast cancer genes BRA1 and BRCA2. She now leads the…
3 A Diet Which Helps You Fit in Your Genes
May 17, 2019 • 29 min
Dr Giles Yeo is a geneticist at the University of Cambridge, a public speaker, TV presenter and the brilliant author behind Gene Eating. We sit down to speak with Giles about how our genetics influence our diet and our behaviour towards food.
2 What One Man Learnt From Over 300 DNA Tests
May 8, 2019 • 32 min
Is Craig one of the most thoroughly DNA tested people on the planet? Quite possibly, but one thing’s for sure, his company ( know a thing or two about a good DNA test. This fascinating discussion with Craig Macpherson explores the…
1 Who are Sano Genetics?
May 3, 2019 • 9 min
If you’re wondering who are Sano Genetics, we’re going to tell you! We’re an ethical genetics research platform who value transparency and patient-centric research. In this episode, Patrick Short (CEO) discusses our platform, our current research projects…