Psychopharmacology and Psychiatry Updates

Psychopharmacology and Psychiatry Updates

psychopharmacologyinstitute.com
Practical updates on psychotropic medications and clinical psychiatry for mental health clinicians.


Pharmacotherapy of Autism Spectrum Disorder: Randomized BAART Clinical Trial
May 14 • 8 min
We review the BAART trial on risperidone vs aripiprazole in irritability associated with autism spectrum disorder.
Antidepressant Safety During Pregnancy: Autism, IQ and Teratogenicity
Apr 28 • 18 min
We discuss studies on the safety of antidepressants in pregnancy regarding autism risk, IQ, cardiac malformations, miscarriage, and neonatal mortality.
Does Prenatal Stress Predispose to Borderline Personality Disorder?
Mar 31 • 7 min
We discuss a study that investigates the relationship between prenatal stress and a diagnosis of borderline personality disorder in offspring.
Clinical Pearls in Perinatal Psychiatry
Mar 12 • 19 min
We explore the case of Rosa, a 36 year old pregnant woman with a history of depression, we discuss how to adjust pharmacotherapy, psychotherapy and other factors to keep in mind.
What Do You Know About Cognitive Enhancers in Depression?
Feb 27 • 7 min
In this podcast episode with Dr. Jim Phelps, we review the evidence for several agents used to help patients with depression and cognitive dysfunction symptoms. We speak about modafinil, vortioxetine, duloxetine and amphetamines.
Can Lithium Prevent Dementia?
Jan 16 • 24 min
In this podcast episode, we delve into the neuroprotective role of lithium in preventing dementia. We review a 2019 randomized controlled trial that administered low-dose lithium to patients with mild cognitive impairment.
Psychopharm in 2019: Your Ultimate Guide
Dec 26, 2019 • 13 min
In this podcast episode, we review the major FDA approvals in psychopharmacology for 2019. We explore brexanolone, bremelanotide, the asenapine skin patch, esketamine, cariprazine, and lumateperone.
Clinical Storytime with Dr. Ken Gillman
Dec 20, 2019 • 22 min
In this podcast episode, we discuss a case of a 65-year-old patient with first-episode MDD that is treatment resistant. With the expertise of Dr. Ken Gillman, we unpack how to manage this case with an MAOI.
Do Antidepressants Increase Risk of Dementia?
Nov 27, 2019 • 6 min
In this podcast episode, we discuss a 2019 study that addresses the question of whether antidepressants increase dementia risk and the possible underlying mechanisms.
Behind the Scenes: Meet Our Team
Nov 15, 2019 • 21 min
In this podcast episode, you get to meet some of the humans of Psychopharmacology Institute. We discuss what we enjoy, what we have to offer and how you can join our team.
“New” Antidepressants? A Quick Takes Episode
Oct 31, 2019 • 8 min
In this podcast episode, Dr. Jim Phelps shares the findings of a tantalizing study that found that agents like allopurinol, angiotensin agents, aspirin and non-steroidals may be effective for the treatment of depression.
Why Don’t We Prescribe MAOIs?
Oct 16, 2019 • 19 min
This episode is the starter pack for the use of monoamine oxidase inhibitors in psychiatry practice. We learn the mechanism of action, food-related instructions and MAOI drug interactions.
Ketamine for Suicidal Ideation: A Quick Take Episode
Oct 2, 2019 • 8 min
In this podcast episode, Dr. Jim Phelps reviews a meta-analysis about ketamine for suicidal ideation and how effective it is.
The Psych Guide to Ketamine and Esketamine
Sep 18, 2019 • 10 min
In this podcast episode we learn the core concepts surrounding ketamine and esketamine; a very hot topic in psychiatry today. We have Dr. Sam Wilkinson and Dr. Joseph Goldberg joining us.
Your Psych Guide To Pharmacogenetic Testing
Aug 28, 2019 • 14 min
In this podcast episode, we dig further into the practical use of pharmacogenetic testing in psychiatric practice. We address its limitations and the resources you can use to guide your decision making.
Do You Order Pharmacogenetic Testing For Your Patients?
Aug 14, 2019 • 16 min
In this podcast episode, we question whether pharmacogenetic testing is valuable in psychiatry practice. Joined by Dr. Simon Kung and Dr. Michael Thase, we find answers to this question!
Podcast: Give Me Some Skin-Transdermal Patches in Psychiatry
Jul 31, 2019 • 15 min
In this podcast interview with Dr. Leslie Citrome, we venture into the topic of transdermal delivery of psychotropics. We explore the challenge of creating patches and also peek into the latest antipsychotics in clinical trials for transdermal delivery.
Podcast: Your Guide to Synthetic Opioids and Bath Salts
Jul 17, 2019 • 19 min
This podcast episode covers the basics of diagnosing and managing novel synthetic opioids and synthetic cathinones.
Designer Drugs: Can You Handle Spice?
Jul 3, 2019 • 15 min
The use of designer drugs (novel psychoactive compounds) is rapidly-growing and dangerous, this podcast episode gives you exactly what you need to know to identify and manage these cases.
What You Need To Know About Psychedelics
Jun 19, 2019 • 18 min
In this podcast episode, we revisit psychedelics with Dr. David Nutt and Dr. Robin Carhart-Harris. We review how psychedelics work, their potential uses, and adverse effects in managing treatment-resistant depression. We also discuss the use of MDMA in…
The Magic of the Serotonin Receptors
May 31, 2019 • 23 min
In this podcast episode, we explore with Dr. David Nutt (Imperial College London) the serotonin receptors 5-HT1A and 5-HT2A and their links to clinical psychiatry. We particularly focus on their roles in mood, anxiety, psychosis, aggression, and learning.
Generalized Anxiety Disorder: What if You Can’t Use An SSRI?
May 16, 2019 • 17 min
In this podcast episode, we answer the question: What if you can’t use an SSRI for GAD? With expert commentary from Dr. David Osser (Harvard Medical School), we explore different options and also highlight what not to use.
Approaching A Case of Generalized Anxiety Disorder: The Basics
May 3, 2019 • 18 min
In this podcast episode, we cover the treatment algorithm of generalized anxiety disorder. Dr. David Osser (Harvard Medical School) shares practical tips and anecdotes for your practice.
How Helpful are Antipsychotic Plasma Levels?
Apr 17, 2019 • 16 min
In this podcast episode, we investigate the effectiveness of using antipsychotic plasma levels in clinical practice with Dr. Jonathan Meyer (University of California San Diego).
Should You Prescribe Natural Medications? Part 2
Apr 8, 2019 • 15 min
In this podcast episode, we learn about prescribing natural medications in psychiatry with Dr. David Mischoulon (Harvard Medical School). We explore the use of melatonin, Valerian and Ginkgo biloba.
How to Prescribe Natural Medications? Part 1
Mar 21, 2019 • 15 min
In this podcast episode, we learn about prescribing natural medications in psychiatry with Dr. David Mischoulon (Harvard Medical School). We explore St. John’s wort, SAM-e, Omega 3 fatty acids and Rhodiola rosea.
How to Manage Adverse Effects of Clozapine – Part 2
Mar 8, 2019 • 13 min
In this episode, we cover practical tips on the management of fever, cardiovascular and cardiometabolic adverse effects related to clozapine use. Dr. Jonathan Meyer provides evidence-based pearls as well as clinical anecdotes.
How to Manage Adverse Effects of Clozapine – Part 1
Feb 21, 2019 • 16 min
In this episode, we cover practical tips on the management of sialorrhea, constipation, sedation, and seizures related to clozapine use. Dr. Jonathan Meyer provides evidence-based pearls as well as clinical anecdotes.
Do SSRIs Increase Bleeding Risk?
Feb 6, 2019 • 13 min
In this episode we answer the question: Do SSRIs increase the risk of bleeding? We do this with Dr. James Levenson (Virginia Commonwealth University) and we explore GIT, perioperative, CNS and postpartum bleeding with SSRIs.
Your Guide to Treating PTSD Comorbidities
Jan 25, 2019 • 11 min
In this episode, we explore the management of common PTSD comorbidities with Prof. David Osser (Harvard Medical School). We cover substance use disorder, depression, psychosis and prescribing in women of childbearing potential.
How to Treat PTSD-Related Sleep Disturbances?
Jan 9, 2019 • 20 min
In this episode, we discuss part of Dr. David Osser’s (Harvard Medical School) PTSD algorithm about treating sleep symptoms of PTSD. We cover the evidence on prazosin’s efficacy and trazodone use. The rationale behind certain drugs to avoid is also…
Prescribing Psychotropics in the Medically Ill
Dec 28, 2018 • 10 min
In this episode, we review principles of prescribing psychotropics in patients with liver, kidney and lung diseases with Dr. James Levenson (Virginia Commonwealth University).
Psychotropics and Gastrointestinal Conditions: Prescribe with the Gut in Mind
Dec 14, 2018 • 16 min
In this episode, we learn to prescribe with the gut in mind. Dr. James Levenson (Virginia Commonwealth University) joins us with to-the-point tips on prescribing psychotropics in patients with GI disease as well as exploring how psychotropics can affect…
Clinical Pearls in Geriatric Psychopharmacology
Nov 29, 2018 • 20 min
In this episode, we uncover clinical pearls of geriatric psychopharmacology. We are joined by Dr. Sandra Jacobson of the University of Arizona giving practical tips on prescribing for this special group of patients.
Treatment-Resistant Depression: Clinical Conundrum
Nov 15, 2018 • 26 min
In this podcast episode, we take on the challenge of treatment-resistant depression and its therapeutic options. Dr. Philip Cowen (University of Oxford) provided insights for this clinical conundrum with a simple algorithm.
How to Manage an Agitated Patient?
Oct 30, 2018 • 17 min
In this episode, we venture into the psychopharmacology of agitation, with a special focus on psychotic agitation. Dr. Michael Jibson (University of Michigan) and Dr. David Osser (Harvard Medical School) shared clinical pearls to treat this challenging…
When to Discontinue Antipsychotics? Reviewing the Evidence
Oct 2, 2018 • 8 min
When is the right time to discontinue an antipsychotic in the treatment of schizophrenia? We reviewed the evidence as well as consulting Dr. Ira Glick to help us answer this question.
Are Drug Interaction Warnings Influenced by Drug Company Promotion? An Interview with Dr. Jeffery Mattes
Aug 27, 2018 • 9 min
Dr. Jeffrey Mattes, psychiatrist in Princeton, New Jersey speaks about drug interaction warnings that appear during electronic prescribing and how these warnings may be influenced by drug company promotion. This interview is part of a series covering the…
Psilocybin for Treatment-Resistant Depression - Dr. Robin Carhart-Harris
Jul 29, 2018 • 14 min
Dr. Robin Carhart-Harris speaks about the use of psilocybin for treatment-resistant depression. - Psilocybin, a psychedelic, is a 5-HT2A agonist. Stimulation of the 5-HT2A receptor promotes neural plasticity -A potential mechanism of action of psilocybin…
Are Psychopharm Algorithms Bad for You?
Jul 29, 2018 • 6 min
At the 2018 Annual Meeting of the American Psychiatric Association, Dr. Robert Patterson (psychiatrist at McLean Hospital Boston) spoke about the benefits of following a structured approach to psychopharmacology. In this episoder, Dr. Patterson explains…