JAMA Clinical Reviews

JAMA Clinical Reviews

jama.jamanetwork.com/journal.aspx
Author interviews that explore the latest clinical reviews.


The Effect of Hearing Loss on Cognitive Decline
May 19 • 18 min
Even limited hearing loss might be associated with cognitive decline. If true, early intervention with hearing aids might help people have better cognitive performance. Michael Johns III, MD, online editor for JAMA Otolaryngology, speaks with Justin…
My Father Was Murdered by Terrorists: Recollections of a Trauma Surgeon
May 5 • 16 min
When she was a teenager Melissa Red Hoffman’s father was killed by terrorists. Dr Hoffman recalls her father’s death and how that has influenced her career and how she can identify with patients and their families at the most difficult moments. Read…
Coronavirus (COVID-19) Update: Ventilatory Management for COVID-Related Respiratory Failure
Apr 24 • 26 min
Management of COVID-19-related respiratory failure differs from what is necessary for ARDS. Rather than having alveolar edema, COVID-19 patients have pulmonary vascular dysregulation. Gas exchange is severely compromised with little reduction in lung…
Parkinson Disease Information for Patients
Apr 14 • 15 min
More than 6 million people worldwide have Parkinson disease. Even though it is classically associated with tremors, the disease has many manifestations and is very treatable for most patients. Michael S. Okun, MD, from the Department of Neurology at…
Coronavirus (COVID-19) Update: Reusing Face Masks and N95 Respirators
Apr 8 • 40 min
Shortages of face masks and N95 respirators have forced clinicians and hospitals to reuse these normally disposable items. Ron Shaffer, PhD, former CDC PPE Research Branch Chief, discusses effective sterilization techniques and how to test that the…
Treating Pediatric Eczema
Apr 7 • 7 min
Eczema is extremely common in children. Most the time it is easily treated with topical steroids but on occasion it requires systemic therapies. JAMA Pediatrics Editor Dimitri Christakis, MD, MPH, and JAMA Network Open Editor Frederick Rivara, MD,…
Coronavirus (COVID-19) Update: Safe Shopping at Stores and Pharmacies
Apr 3 • 19 min
Food and medicine shopping is essential during the COVID-19 pandemic, but requires getting out and standing close to strangers at a time when social distancing and sheltering-in-place are recommended to slow spread of disease. David Aronoff, MD,…
Coronavirus Disease 2019 (COVID-19) Update: PCR Testing and Shortages
Mar 27 • 31 min
The lack of availability of COVID-19 testing has interfered with the ability to contain the spread of disease. Omai Garner, PhD, laboratory director for Clinical Microbiology in the UCLA health system, explains how PCR testing for COVID-19 works and…
Coronavirus Disease 2019 (COVID-19) Update: How the VA Is Preparing
Mar 25 • 17 min
As COVID-19 spreads, clinicians and health systems are struggling to prepare for a surge of patients. Richard Stone, MD, the US Veterans Health Administration’s Executive in Charge, spoke with JAMA about how the VA health system is preparing for this…
Coronavirus (COVID-19) Update: Lessons Learned From The 2003 SARS Outbreak
Mar 25 • 38 min
In 2003, Toronto was the North American center for Severe Acute Respiratory Syndrome (SARS). The disease spread through the city’s hospitals before anyone knew what was happening. Dr Allison McGeer was a clinician caring for SARS patients and…
Coronavirus (COVID-19) Update: Chloroquine/Hydroxychloroquine and Azithromycin
Mar 24 • 17 min
Chloroquine was shown in 2004 to be active in vitro against SARS coronavirus but is of unproven efficacy and safety in patients infected with SARS-CoV-2. The drug’s potential benefits and risks for COVID-19 patients, without and with azithromycin, is…
Nonalcoholic Steatohepatitis: The Primary Care Perspective
Mar 24 • 15 min
Nonalcoholic steatohepatitis (NASH) is becoming more frequent as the population becomes more obese. This is not a benign problem, and NASH can ultimately lead to cirrhosis and liver failure. It is thought that NASH will ultimately become the most…
The Diagnosis and Management of Primary Hyperparathyroidism
Mar 24 • 19 min
Hyperparathyroidism is a fairly common disease that causes elevated calcium levels and bone depletion, resulting in fractures and kidney problems. There are medications that can effectively manage hyperparathyroidism, and in some cases surgery is…
Coronavirus (COVID-19) Update: Early Safety Signals Around Ibuprofen and Renin-Angiotensin Inhibitors
Mar 20 • 9 min
Emerging information about how SARS-CoV-2 virus infects cells has led to speculation that NSAIDs and ACE inhibitors/angiotensin receptor blockers (ARBs) may worsen clinical disease. Infectious disease physician Carlos del Rio, MD, of Emory University…
Who Was Nathan Pritikin and Why Is There a Diet Named After Him?
Mar 17 • 23 min
This podcast explains the Pritikin diet to patients. Nathan Pritikin was a college dropout who became an entrepreneur. While doing research for the government during World War II, he observed that populations that had extremely limited food…
Nathan Pritikin and His Diet
Mar 17 • 23 min
Nathan Pritikin was a college dropout who became an entrepreneur. While doing research for the government during World War II, he observed that populations that had extremely limited food availability because of the war had substantially reduced…
COVID-19 in Seattle: Clinical Features and Managing the Outbreak
Mar 15 • 24 min
Seattle was one of the first US cities to have a COVID-19 outbreak, with a cluster of nursing home-related deaths. However, many people who tested positive for the novel coronavirus never became ill, and in some the clinical illness was…
The Effect of the COVID-19 Pandemic on Clinic Operations
Mar 13 • 20 min
Seattle has been a focal point for the US in the coronavirus pandemic. Doug Paauw, MD, professor of medicine at the University of Washington, in Seattle, describes the UW primary care clinic experience as this pandemic evolved. Major lessons learned…
Update on Coronavirus: March 6, 2020, by NIAID’s Anthony Fauci, MD
Mar 9 • 33 min
Coronovirus (the virus SARS-CoV-2) continues to spread throughout the world. In recent weeks, there has been an increasing number of cases and deaths in the US. As concern about the virus increases, there is an increasing need for accurate information…
Unprofessional Behavior Leads to Complications
Feb 25 • 10 min
Physicians who act out cause all sorts of problems. Fortunately, only a few clinicians have behavior problems and in the modern era, bad behaviors are not tolerated. Bad behaviors get reported these days and actions are taken against these sorts of…
The 2020 Influenza Epidemic—More Serious Than Coronavirus in the US
Feb 18 • 31 min
Although coronavirus disease 2019 (COVID-19) dominates the news in early 2020, it affects few people in the US. In contrast, at the same time the US is experiencing a severe influenza epidemic, which has caused an estimated 250 000 hospitalizations…
AIDS-Related Chronic Inflammation Leading to Chronic Disease
Feb 18 • 9 min
Great strides have been made in treating HIV, as Anthony Fauci, MD, discusses in this podcast episode. But even substantial viral suppression leaves some virus behind, causing chronic inflammation. Many chronic diseases, including atherosclerotic…
Parkinson Disease
Feb 11 • 26 min
More than 6 million people worldwide have Parkinson disease. Even though it is classically associated with tremors, the disease has many manifestations and is very treatable for most patients. Michael S. Okun, MD, from the Department of Neurology at…
Testing for Breast Cancer Susceptibility Genes
Feb 11 • 13 min
Breast cancer is a leading cause of death in women. Some women have a cancer susceptibility gene known as BRCA, and women should be tested for BRCA under some circumstances. Carol Mangione, MD, division chief of General Internal Medicine and Health…
Management of Chronic Stable Angina in 2020
Feb 4 • 7 min
Controversy exists regarding how to best manage chronic stable angina. Intuitively, it seems that because it is usually caused by coronary artery lesions, addressing those lesions either via percutaneous coronary angiography or coronary artery bypass…
Treating Conjunctivitis and Dry Eye Disease
Feb 4 • 18 min
Conjunctivitis and dry eye disease are some of the most common conditions patients present with. They are usually benign entities that respond well to conservative measures and usually don’t require medications. However, if medications are…
2019 Novel Coronavirus: An Update From NIAID Director Anthony Fauci, MD
Jan 30 • 8 min
A new virus known as the 2019 novel coronavirus (2019-nCoV) is rapidly spreading through China. The rapid spread and severity of this illness are worrisome and the possibility that it develops into a pandemic is very real. Anthony Fauci, MD, director…
Football Players and Erectile Dysfunction Associated With Repetitive Head Injury
Jan 29 • 7 min
American football is a dangerous sport and is characterized by violent contact between people that often leads to repetitive head injury. A multitude of health effects may result from this sort of head injury, but a new finding reported in the…
The Keto Diet: Advice for Patients
Jan 28 • 9 min
The keto diet is very popular and involves eating very few carbohydrates, a fair amount of fat, and normal amounts of protein. It is one of many ways to lose weight. David Heber, MD, formerly the chair of Clinical Nutrition at UCLA, explains the keto…
The Keto, Atkins, and Pritikin Diets
Jan 28 • 15 min
There are many named diets that receive a great deal of attention. But what are they and do they work? David Heber, MD, PhD, from the UCLA Center for Human Nutrition explains these diets. Related articles:
The American Heart Association Takes a Stance Against e-Cigarettes
Jan 21 • 7 min
e-Cigarettes are dangerous, but the public has been falsely led to believe that they are safe. Because of this misconception and the inherent dangers, the American Heart Association (AHA) has taken an aggressive stance to educate the public about…
An Inconvenient Tooth
Jan 14 • 44 min
Animal bites can be a cause of significant injury and on occasion, fatalities. In this episode, JAMA Fishbein Fellow Angel Desai, MD, MPH discusses the prevention, treatment, and epidemiological oddities of animal bites with Dr Sandra Nelson,…
NICE Guidelines for Heavy Menstrual Bleeding: What to Make of Them
Dec 19, 2019 • 20 min
The UK’s National Institute for Health and Care Excellence (NICE) recently issued guidelines for how to manage heavy menstrual bleeding. Guidelines only provide guidance and they must be interpreted for an individual patient’s clinical context….
The Medical and Political Response to the 2019 Christchurch Mosque Mass Shooting
Dec 10, 2019 • 26 min
On March 15, 2019, a lone gunman walked into 2 mosques within minutes of each other in Christchurch, New Zealand, and opened fire with semiautomatic weapons, killing 51 and wounding many more. We spoke to Greg Robertson, MB ChB, the surgeon who…
What Do I Need to Know About e-Cigarettes and If They Help People Stop Smoking?
Nov 25, 2019 • 17 min
Electronic cigarette (e-cigarette) use, otherwise known as “vaping,” has been increasing since 2010. This podcast reviews research on the epidemiology and possible adverse health effects of e-cigarette and nicotine use, and the pitfalls associated…
The Underappreciated Problem of Cardiac Disease in Women
Nov 18, 2019 • 10 min
Barbra Streisand and Noel Bairey Merz, MD, director of the Streisand Women’s Heart Center at Cedars-Sinai in Los Angeles, California, discuss the problem of cardiovascular disease in women and especially coronary microvascular disease, which causes…
Review of Atrial Fibrillation Treatment
Nov 12, 2019 • 25 min
Atrial fibrillation is a very common problem that is treated with a variety of medications and interventions. Sandip Mukherjee, MD, a contributing editor to The Medical Letter, is the Medical Director of Physician Liaison Services with the Office of…
Influenza Vaccination in 2019-2020
Nov 6, 2019 • 13 min
Winter is coming…and with it, the onset of flu season. In this episode, Jean-Marie Pflomm, PharmD, Editor in Chief of The Medical Letter, decodes flu vaccines: trivalent vs quadrivalent, live attenuated vs inactivated, and much more.
How Adolescent Boys’ Need for Friendship Affects Their Mental Health
Nov 5, 2019 • 37 min
Adolescent boys are notoriously difficult to deal with. However, some of their behaviors mask a need they have for developing intimate friendships. Being adolescent boys living in a macho culture, many deny that they need these relationships. Niobe…
Emerging Applications for Ketamine
Oct 22, 2019 • 25 min
Even though it gained notoriety for recreational uses, Ketamine is experiencing a resurgence in clinical settings given its versatility and potential applications, including for pain treatment and depression. David Juurlink, MD, from Sunnybrook Health…
Understanding Lipids and Cardiovascular Risk Through Mendelian Randomization
Oct 8, 2019 • 27 min
Mendelian randomization is a powerful technique that enables investigators to mimic randomized clinical trials by characterizing genetic differences between groups of people and studying their clinical outcomes. Brian A. Ference, MD, MPhil, from the…
Pancreatic Cancer
Oct 8, 2019 • 26 min
Pancreatic cancer is the third most common cause of cancer death in the United States. Timothy Donohue, MD, chief of surgical oncology at the University of California, Los Angeles, provides an overview of the disease. Read the articles:
Personal Protective Equipment for Health Care Infection Control
Oct 7, 2019 • 19 min
Personal protective equipment comprises gloves, gowns, masks, regular respirators, and powered air purifying respirators (PAPRs). In this Clinical Review podcast Trish Perl, MD, of UT Southwestern Medical Center reviews the indications for each and…
Improving Uptake of Preexposure Prophylaxis (PrEP) for HIV in Primary Care
Oct 6, 2019 • 11 min
JAMA Fishbein Fellow Angel Desai, MD interviews Douglas S. Krakower, MD at the IDWeek 2019 conference in Washington, D.C. Related article:
Update in Clinical Infectious Diseases 2019-2020
Oct 5, 2019 • 14 min
This Clinical Review podcast reviews some of the most important advances in clinical infectious diseases presented at IDWeek 2019 including data on rapid testing, new antimicrobial agents, and new strategies for using existing antibiotics to manage…
A New Path for Gun Research Funding
Sep 10, 2019 • 16 min
Since the passage of the Dickey Amendment in 1996, federal funding for gun violence research has been withheld from the CDC and other federal agencies that should be tasked with figuring out the origins and solutions to this problem. But while the US…
Bariatric Surgery and Cardiovascular Outcomes in Patients With Type 2 Diabetes and Obesity
Sep 3, 2019 • 14 min
JAMA Deputy Editor Ed Livingston, MD, interviews Steven Nissen, MD, at the European Society of Cardiology’s 2019 conference in Paris, France.
Management of Heart Failure in 2019-2020, Part 2
Sep 2, 2019 • 11 min
JAMA Deputy Editor Ed Livingston, MD, interviews James Januzzi, MD, at the European Society of Cardiology’s 2019 conference in Paris, France.
Management of Heart Failure in 2019-2020, Part 1
Sep 2, 2019 • 16 min
JAMA Deputy Editor Ed Livingston, MD, interviews Akshay Desai, MD, at the European Society of Cardiology’s 2019 conference in Paris, France.
The Influence of Obesity on Cancer
Aug 20, 2019 • 20 min
Jennifer A. Ligibel, MD, from the Dana-Farber Cancer Institute and Harvard Medical School, Boston, explains how obesity influences the risk of developing cancer and how it influences the prognosis of existing cancer.
Responsible Use of Opioids to Treat Cancer Pain
Aug 6, 2019 • 29 min
Dr. Eduardo Bruera, Chair of the Department of Palliative Care at MD Anderson, discusses how to responsibly manage cancer pain using opioids.
Diagnosing Menopause
Jul 22, 2019 • 15 min
Menopause is inevitable for women. It symptoms are uncomfortable and distressing. For women to best cope with menopause, it is useful to firmly establish the onset so that appropriate counseling can follow. In this podcast, an expert in this field,…
Guns and Suicide
Jul 16, 2019 • 27 min
Using firearms to commit suicide is one of the most common causes of firearm related deaths. This can happen even in families where it seems highly unlikely to occur. In this podcast, we tell the story of a policeman’s daughter who got a hold of his…
Subclinical Hypothyroidism
Jul 9, 2019 • 16 min
Subclinical hypothyroidism is common, but it is not clear how best to treat it. Anne R. Cappola, MD, ScM, professor of medicine at the University of Pennsylvania, explains how to manage this important clinical condition. Read the article:
The Clinical Ramifications of Dense Breasts
Jul 2, 2019 • 23 min
There are now 36 states and recent federal legislation that require that clinicians inform women about breast density results from mammography. Consequently, clinicians must be aware of the clinical ramifications of dense breasts and what to do about…
California’s Attempt to Improve Measles Vaccination Rates
Jul 2, 2019 • 19 min
California enacted 3 aggressive laws between 2014 and 2016 in an effort to improve measles vaccination rates. To a large extent these laws were effective in increasing vaccination rates, but some of the improvements were offset by clinicians granting…
Reducing the Intensity of Antiplatelet Therapy Following Coronary Stent Procedures
Jun 25, 2019 • 11 min
A conversation with Greg Curfman, MD, JAMA Deputy Editor and a cardiologist, who reviews 2 new studies showing that a short duration of dual antiplatelet therapy may not result in more myocardial ischemic events. Read the article:
The Gabby Giffords Shooting
Jun 11, 2019 • 32 min
Over the span of less than a minute, a gunman with a history of mental health issues turned a Safeway parking lot into the scene of a mass shooting, killing 6 and wounding 13 in 20 seconds. In this inaugural episode of the In Our Lane podcast series,…
Abnormal Uterine Bleeding
Jun 4, 2019 • 34 min
Andrew M. Kaunitz, MD, from the Department of Obstetrics and Gynecology at the University of Florida, Jacksonville, explains how to diagnose and treat various patterns of abnormal uterine bleeding. Read the article:
Menopausal Hormone Therapy
May 30, 2019 • 29 min
Jan L. Shifren, MD, from the department of obstetrics and gynecology, Massachusetts General Hospital, and Harvard Medical School discusses menopausal symptoms such as hot flashes and how they can be effectively treated by the administration of…
Cervical Cancer Screening
May 28, 2019 • 9 min
George F. Sawaya, MD, professor of obstetrics and gynecology at the University of California, San Francisco, discusses cervical cancer screening in the modern era. Read the article:
Treating Nonmetastatic Breast Cancer in 2019
May 7, 2019 • 29 min
Breast cancer outcomes continue to improve. Treatments for the disease are very effective and continually evolving. We spoke with Patricia A. Ganz, MD, from UCLA about what is new in breast cancer treatment.
JAMA Women’s Health Series Introduction by Dr Carolyn Crandall
May 7, 2019 • 2 min
Dr Carolyn Crandall, professor of medicine at the David Geffen School of Medicine at UCLA and JAMA Associate Editor, introduces JAMA’s new series of articles on women’s health.
Beyond the Rhetoric: Gun Control That Works, Part 3
Apr 9, 2019 • 25 min
Congressman Mike Thompson chairs the US House Gun Violence Prevention Taskforce. He spoke with us about what the House has done to address gun violence and what you can do to help them see necessary legislation make it into law. We also talk with…
How to Reduce Maternal Mortality Rates in the United States
Apr 2, 2019 • 27 min
Maternal mortality rates in most of the United States are high. These rates were successfully lowered in the United Kingdom and also in California. Many of these deaths are preventable. In this podcast we interview Elizabeth A. Howell, MD, MPP, from…
Beyond the Rhetoric: Gun Control That Works, Part 2
Mar 26, 2019 • 26 min
Almost nothing is more controversial than gun control in the United States. Yet while passions flare and legislators posture but do little, deaths from gun violence are all too common. Almost every proposal put forward to address gun violence…
Update on Atrial Fibrillation: Review of the New AHA/ACC/HRS Treatment Guidelines
Mar 15, 2019 • 42 min
Cardiologist and JAMA Deputy Editor Greg Curfman, MD, discusses the many changes in the new AHA/ACC/HRS atrial fibrillation guidelines with University of Chicago cardiologists Gaurav Upadhyay, MD, and Francis Alenghat, MD, PhD. Major changes include…
Beyond the Rhetoric: Gun Control That Works, Part 1
Mar 12, 2019 • 27 min
Almost nothing is more controversial than gun control in the United States. Yet while passions flare and legislators posture but do little, deaths from gun violence are all too common. Almost every proposal put forward to address gun violence…
Is It Safe? What Happens When Your Surgeon Is Not Actually Doing Some of Your Operation?
Feb 26, 2019 • 24 min
Great controversy exists regarding the safety of surgery when the attending surgeon allows someone else to perform parts of the operation. These practices are necessary components of surgical training, but how safe this is for patients remains…
COPD: All You Need to Know in 20 Minutes
Feb 26, 2019 • 21 min
COPD is common enough that it is responsible for 3% of all clinic visits in the United States. Clinicians will undoubtedly deal with this disease in their practice. How to diagnose and manage it is reviewed by Frank C. Sciurba, MD, a professor of…
Next Generation Sequencing of Infectious Pathogens in Public Health and Clinical Practice
Feb 14, 2019 • 25 min
Next-generation sequencing is a catchall term for new, high-throughput technologies that allow rapid sequencing of a full genome. It can be used to sequence a patient’s DNA in diagnosing a genetic disorder or characterizing a cancer, but can also be…
Can I Believe the Results From Observational Studies? Using E-Values That Anyone Can Calculate for Evaluating the Risk of Confounding
Feb 12, 2019 • 28 min
E-values are a new tool that enables investigators to estimate the likelihood that some unmeasured confounder might overcome seemingly positive results. They are very easy to calculate and any reader of the medical literature can do this calculation…
Finding a Serious Arrhythmia Using a Watch
Jan 29, 2019 • 14 min
Saved by a Fitbit. Technology is developing at a pace far exceeding its application in medical care. An exception is in consumer devices, which as long as they do not hold themselves out as diagnostic tools, can apply as many technologies to wearable…
Screening for Breast Cancer: Is It Worth It?
Jan 22, 2019 • 17 min
Breast cancer screening is debated passionately among those who advocate for very aggressive screening and other experts who believe that screening can be harmful. The arguments for all sides of the debate are best understood by knowing the numbers of…
Major Societies Agree – A New Approach to Penicillin Allergy Is Needed
Jan 15, 2019 • 35 min
Very few people who think they are allergic to penicillin actually are. Yet, even if someone reports a remote and vague history of penicillin allergy, these very useful medications will not be given. This forces many patients to use antibiotics that…
Medical Emergencies While Flying
Dec 21, 2018 • 29 min
When flying and they call “Is there a licensed medical professional on board,” should physicians respond? If so, what should they do? Are they liable if things go wrong? We interview Christian Martin-Gill, MD, MPH, Department of Emergency Medicine,…
Bayes for Clinicians Who Need to Know but Don’t Like Math
Dec 11, 2018 • 28 min
The statistical concept of Bayes comes up in clinical medicine all the time. It simply means that what you know about something factors into how you analyze it. This contrasts with the commonly used statistical approach called frequentist analysis of…
Battle of the Heart Societies, Part 2: Who Is Right – the US or Europe Regarding How to Manage Hypertension? Their Differences
Nov 20, 2018 • 38 min
Within the last 2 years, major guidelines have been issued from US-based and European organizations that differ in their recommendations for the diagnosis and treatment of hypertension. Experts from both sides of the Atlantic—Paul Whelton, MD, from…
A Family’s Struggle With Alcoholism
Nov 13, 2018 • 31 min
What is it like to go through alcohol withdrawal at home? What is it like for a mother to sit by her son’s side while he goes through withdrawal and supporting him? Why does someone who doesn’t have any particular reason to drink misuse alcohol? The…
Battle of the Heart Societies: Who Is Right – the US or Europe Regarding How to Manage Hypertension?
Nov 6, 2018 • 32 min
Within the last 2 years, major guidelines have been issued from US-based and European organizations that differ in their recommendations for the diagnosis and treatment of hypertension. Experts from both sides of the Atlantic—Paul Whelton, MD, from…
Observations From ICU Patients We Thought Were Asleep, but Were Not
Oct 23, 2018 • 25 min
What if the patient you are managing in the ICU is not asleep when you thought they were? Patients relate their very disturbing stories about what they experienced while in an ICU and their treating clinicians thought they were asleep.
An Update on the Diagnosis and Treatment of Venous Thromboembolic Disease
Oct 16, 2018 • 17 min
Venous thromboembolic disease is common. There are many steps necessary to establish a diagnosis or treat this disease. These are summarized in this JAMA Clinical Reviews podcast and interview with Philip S. Wells, MD, from the Department of Medicine,…
Alcohol Withdrawal Syndrome
Oct 2, 2018 • 20 min
Alcohol withdrawal is a serious problem that can lead to mortality. How to predict if it will occur when a patient who is misusing alcohol is admitted to the hospital is challenging. This Rational Clinical Examination article reports results of a…
Treating Appendicitis Without Surgery – 5-Year Follow-up From a Randomized Clinical Trial of Antibiotic Treatment
Sep 25, 2018 • 29 min
In 2015, JAMA published results of a randomized clinical trial showing that antibiotic treatment for acute appendicitis was feasible. Doubters of the efficacy of antibiotics for treating appendicitis were concerned about what the long-term recurrence…
Treating Lyme Disease in 2018, Part 2
Sep 18, 2018 • 29 min
There are new findings about another form of Borrelia: Borrelia miyamotoi. This form of Borrelia causes a relapsing fever but is spread in the same way that Lyme disease is. To help understand these new findings we spoke with Eugene Shapiro, MD, from…
Treating Lyme Disease in 2018, Part 1
Sep 11, 2018 • 24 min
In this JAMA Clinical Reviews podcast, we talk to Eugene D. Shapiro, MD, from Yale University School of Medicine for an update on Lyme disease, including new ideas about its diagnosis and treatment.
What you need to know about syphilis in 2018
Sep 4, 2018 • 30 min
Syphilis is on the rise despite prior successful efforts to control it. Why is it coming back and what needs to be done about it? Dr Charles Hicks from UC San Diego explains. This podcast coincides with updated syphilis screening recommendations from…
Treating Alcohol Use Disorder
Aug 28, 2018 • 23 min
Up to 7% of the entire US population has alcohol use disorder. It’s important for every clinician to understand how to approach patients to question them about their use of alcohol and to establish a diagnosis when alcohol use disorder is present….
Saving Lives by Stopping Bleeding
Aug 14, 2018 • 21 min
Bleeding is one of the most common preventable causes of death. It is common, yet most people don’t know what to do about it when they see it. The Stop the Bleed campaign is an effort to educate the public should they encounter people who are…
Working on the Precipice: On the Frontlines of the AIDS Epidemic at the CDC, Part II
Aug 1, 2018 • 26 min
As the AIDS crisis unfolded, each discovery seemed to lead to a new mystery. Who was at risk? Why was this disease of immune activation so hard for the body to fight? Most important, what could be done to stop it? In the conclusion of this JAMA…
Working on the Precipice: On the Frontlines of the AIDS Epidemic at the CDC, Part I
Jul 24, 2018 • 24 min
When AIDS first appeared in the gay community in 1981, it was terrifying for patients and clinicians alike. Nobody knew exactly what was going on. But using basic epidemiologic methods, a small team of public servants at the CDC raced against the…
Return of the IUD: Long-acting Reversible Contraception Is Safe and Effective
Jul 6, 2018 • 26 min
Misplaced fears about IUDs have caused them to be avoided by many women, despite the fact that they are very safe and among the most effective means for contraception. In this JAMA Clinical Reviews podcast, we review long-acting reversible…
Health Care Spending Gone Wild: Using Expensive Insulin Analogs With Few Clinical Advantages
Jun 23, 2018 • 27 min
Health care spending in the United States is out of control. The most significant aspect of medical care driving this spending is pharmaceuticals; within pharmaceuticals the greatest increases have been in spending for diabetes medications. The cost…
A Goal Too Far: Rethinking HbA1c Targets for Diabetes Treatment
Jun 19, 2018 • 29 min
The American College of Physicians just changed its guidance for how aggressively to treat type 2 diabetes, relaxing the HbA1c goal to something below 8 rather than 6.5 or 7 as other organizations recommend. This has stirred up substantial…
When Will It Stop? Clinicians Are Still Ordering Routine ECGs Despite Recommendations to the Contrary
Jun 12, 2018 • 22 min
For many years guidelines have recommended against obtaining ECGs for low-risk patients undergoing routine health examinations. Yet about a fifth of all patients having these exams get an ECG. Why? Are clinicians just stubborn or uninformed or are the…
Replacing the Trachea: An Exciting New Procedure; But How Do We Know It Really Works?
May 20, 2018 • 21 min
Many attempts to replace the trachea have failed in the past. The most spectacular failure was fraudulent research done in Europe by a high-profile surgeon who was eventually charged with scientific misconduct. JAMA now reports a clinical series of…
Update: New Recommendations for Prostate Cancer Screening
May 8, 2018 • 25 min
The controversy continues about the efficacy of PSA screening for prostate cancer. New recommendations were just issued from the USPSTF about who should be screened for prostate cancer and when. But not everyone agrees with these recommendations….
Peanut Allergy: The Recommendations Have Changed
Mar 6, 2018 • 19 min
Peanut allergy is common. But it is more common in countries that delay the introduction of peanuts into the diets of infants. Guidelines in the United States previously recommended delayed introduction of peanuts for infants, which resulted in an…
What Is New in Acute Respiratory Disease Syndrome?
Feb 20, 2018 • 30 min
Acute respiratory disease syndrome is characterized by respiratory failure that occurs after someone is acutely ill, usually from a disease that does not primarily involve the lungs. Its cause, diagnosis, and treatment are reviewed in this JAMA…
Medical Findings In U.S. Government Personnel Reporting Symptoms After Exposure To Sensory Phenomena in Havana, Cuba
Feb 14, 2018 • 29 min
Douglas H. Smith, MD, of the University of Pennsylvania’s Department of Neurosurgery and Center for Brain Injury and Repair, and Randel Swanson II, DO, PhD, of the University of Pennsylvania’s Physical Medicine and Rehabilitation department, summarize…